Cart
sales@molnova.com
Home - Products - Membrane Transporter/Ion Channel - Sodium Channel - GX 201

GX 201

CAS No. 1788071-27-1

GX 201( —— )

Catalog No. M37645 CAS No. 1788071-27-1

GX 201 is a selective NaV1.7 inhibitor, IC50 of < 3.2 nM for hNaV1.7.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 163 Get Quote
5MG 250 Get Quote
10MG 377 Get Quote
25MG 609 Get Quote
50MG 877 Get Quote
100MG 1188 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    GX 201
  • Note
    Research use only, not for human use.
  • Brief Description
    GX 201 is a selective NaV1.7 inhibitor, IC50 of < 3.2 nM for hNaV1.7.
  • Description
    GX-201 is a selective NaV1.7 inhibitor, with an IC50 of <3.2 nM for hNaV1.7.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Wild-Type Mice.Dosage:0.3, 1, 3 mg/kg.Administration:Orally, once.Result:Produced a dose-dependent inhibition of the nociceptive events.
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    Sodium Channel
  • Recptor
    Sodium Channel
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1788071-27-1
  • Formula Weight
    563
  • Molecular Formula
    C25H27ClF4N2O4S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 62.5 mg/mL (111.01 mM; Ultrasonic )
  • SMILES
    CS(=O)(=O)NC(=O)c1cc(C2CC2)c(OCC2CCN(Cc3cc(ccc3Cl)C(F)(F)F)CC2)cc1F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Girish Bankar, et al. Selective Na V 1.7 Antagonists with Long Residence Time Show Improved Efficacy against Inflammatory and Neuropathic Pain. Cell Rep. 2018 Sep 18;24(12):3133-3145.?
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Benzonatate

    Benzonatate is an antagonist of sodium channel protein.Na(+) currents are inhibited most potently by a benzonatate fraction containing the 9-ethoxy component.?

  • NaV1.7 inhibitor-1

    NaV1.7 inhibitor-1, an efficacious inhibitor of voltage-gated sodium channel (NaV) 1.7 (IC50 of 0.6 nM for hNaV1.7).

  • SB-237376

    SB-237376 is a calcium and potassium channel antagonist used to treat cardiac arrhythmias.

Sign In Join Free